Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway
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چکیده
منابع مشابه
Oridonin Attenuates Aβ1–42-Induced Neuroinflammation and Inhibits NF-κB Pathway
Neuroinflammation induced by beta-amyloid (Aβ) plays a critical role in the pathogenesis of Alzheimer's disease (AD), and inhibiting Aβ-induced neuroinflammation serves as a potential strategy for the treatment of AD. Oridonin (Ori), a compound of Rabdosia rubescens, has been shown to exert anti-inflammatory effects. In this study, we demonstrated that Ori inhibited glial activation and decreas...
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ژورنال
عنوان ژورنال: Biomolecules & Therapeutics
سال: 2020
ISSN: 1976-9148,2005-4483
DOI: 10.4062/biomolther.2019.123